Writer-director brothers Jay and Mark Duplass are among the rarefied group of mumblecore film-makers who have managed to escape their DIY roots...largely with the help of professional actors.
Cyrus saw them step into the mainstream spotlight with Jonah Hill, Marisa Tomei and John C Reilly wryly lending weight to a terrific script and a knockout premise.
This time out Judd Apatow protégé Jason Segel takes centre stage as Jeff, a stay-at-home stoner 30-something doted on by his disappointed mum (Sarandon, superb) and despised by his outwardly successful Porsche-owning older brother Pat (Helms).
However, the good-natured Jeff - who it seems most is happy spending his time smoking weed in the basement - turns out to be a rather decent fellow while his spivvy sibling demonstrates that aspiration doesn't necessarily mean happiness, least of all for his long-suffering wife (Greer).
That the reversal of assumed roles takes place over the course of a few hours is a testament to the writing skills of the Duplass brothers, who imbue proceedings with a warmth and generosity of spirit.
Dyed-in-the-wool mumblecore fans will accuse the brothers of selling out...but for the rest of us it's sweet and - ultimately - rather moving.